College of pharmacy, ootacamund, tamil nadu, india. Rapid hplcpda estimation of swertiamerin in extracts of. Phytochemical and pharmacognostic value of enicostemma. Invitro antiinflammatory activity was evaluated using albumin denaturation assay, proteinase inhibitory activity, membrane stabilization, and antilipoxygenase activity at different concentrations. Plant details information about enicostema axillare plant. Save nature to survive hepatoprotective activity of.
Abstract of research paper on biological sciences, author of scientific article ramaiyan dhanapal, j. Phloretin is a natural chalcone with antibacterial and antiinflammatory effects. Morphological, anatomical and molecular investigation into. Enicostema axillare wikispecies, free species directory. Pdf mamejvo enicostemma axillare raynal is a perennial herb with diversified health benefits. It has drawn the attention of pharmaceutical companies to turn towards the herbal products, having fewer side effects. Hepatoprotective activity of enicostemma axillare in carbon tetrachloride induced hepatotoxicity in albino rats. List of various diseases cured by enicostemma axillare. Biogenic synthesis, characterization and pharmacological. To remove any free biomass residue or compound that is not the capping ligand of the nanoparticles, the residual solution of 100 ml after. Its ethyl acetate extract has shown potent in vitro antioxidant activity and found to contain 7. In vitro antioxidant activity of enicostemma axillare semantic scholar. They concluded that active phytoconstituents was responsible for prominent antioxidant and antimicrobial activity showed by enicostemma axillare. No systematic toxicity study was described for this plant and hence the present was undertaken to evaluate acute and subacute toxicity of aqueous extract of enicostemma axillare aeea.
These plants were selected to evaluate their potential antibacterial activity. Pdf in vitro antiinflammatory activity of methanol. The leaves extracts of enicostemma axillare are used in traditional medicine for treatment of various infections. Improved and rapid hplcpda method for identification and quantification of swertiamarin in the aerial parts of enicostemma axillare virendra singh rana, tushar dhanani and satyanshu kumar directorate of medicinal and aromatic plants research indian council of agricultural research, boriavi387 310, anand, gujarat, india. Issn 22293566 phytochemical screening of plant of enicostemma axillare zaheer zahid, deshpande sagar d. Green synthesis of silver nanoparticles using gymnema. In vitro antioxidant activity of enicostemma axillare. Evaluation of bioactive potential of enicostemma axillare 177 curado mp, edwards b, shin hr, strom h, ferlay j, heanue m, et al. Preliminary phytochemical analyses were carried out in different extracts of enicostemma axillare ea like hexane, chloroform, ethyl acetate and 85 % methanol.
In the present article, the facile green synthesis of silver nanoparticles agnps using aqueous leaf extract of enicostemma axillare lam. Henry lindlahr nature cure pdf nature cure henry lindlahr on free shipping on qualifying offers. Swertiamarin, a secoiridoid isolated from the ethyl acetate extract of enicostemma axillare, was evaluated for antiedematogenic activity using carrageenan, formalin, and histamineinduced paw edema methods in rats. Antibacterial activity of plants used in indian herbal. This is a simple, costeffective, stable for a long time and reproducible aqueous synthesis method to obtain a selfassembly ag nanoparticles. Pdf antinociceptive activity of swertiamarin isolated. This is a simple, costeffective, stable for a long time and reproducible aqueous synthesis method to obtain a. Molecules free fulltext target proteins of phloretin. Pdf traditional medicine system of india comprised varieties of plants which are playing a. Abstract objective to evaluate the possible antifertility activity of enicostemma axillare e.
Antiulcer and antiinflammatory activity of aerial parts enicostemma. Locally it is known as chota chirayita and used in indigenous medicines in the treatment of fevers and as bitter tonic and forms hypoglycemic marketed formulations. Molecular docking of swertiamarin on telomerase targets pdb id. Gentianaceae was assessed for its antiinflammatory activity by invitro methods. Preliminary study on antifertility activity of enicostemma axillare leaves and urena lobata root used in indian traditional folk medicine. The plant is used in folk medicine to treat diabetes. Uses, benefits, cures, side effects, nutrients in enicostemma axillare. Phytochemical profiling, antibacterial potential and gcms analysis of methanol leaf extract of enicostemma axillare k. Enicostemma axillare ea is used as a laxative, antiinflammatory and also as. Lam raynal synonym enicostemma littorale blume, gentianaceae is a. Department of agriculture agricultural research service. Enicostemma axillare belongs to family gentianaceae is a perennial herb found in through out india and common in costal areas.
The results showed that enicostemma axillare methanol extract. Antinociceptive activity of swertiamarin isolated from enicostema axillare. In the carrageenaninduced method, the percentages of edema inhibition obtained after 5 h induction were 38. The present communication deals with the pharmacognostic evaluation on the different. Issn phytochemical and antimicrobial evaluation of plant. Locally it is known as chota chirayita and used in indigenous medicines in the treatment of fevers and as bitter tonic and forms one of ingredients of many hypoglycemic marketed formulations. Download pdf international journal of pharmaceutical and. Hepatoprotective activity of enicostemma axillare in.
Molecular docking, antiproliferative and anticonvulsant. Drawing techniques for graphic communication in architecture and building. Differentiated ilcc were initially incubated for 30 min in glucosefree krebsringer bicarbonate buffer. Antiedematogenic and free radical scavenging activity of swertiamarin isolated from enicostemma axillare. Click and collect from your local waterstones or get free uk delivery on orders over. Antiinflammatory, antioxidants, antiulcer, enicostemma littorale. Delonix elata, enicostemma axillare, merremia tridentata, mollugo cerviana and solanum incanum are medicinal plants used in traditional indian medicine for the treatment of various ailments.
Evaluation of bioactive potential of enicostemma axillare 98 introduction oxidative stress depicts the existence of products called free radicals and reactive oxygen species ros, which are formed under normal physiological conditions but become deleterious when not being eliminated by the endogenous systems. Swertiamarin, a secoiridoid isolated from the ethyl acetate extract of enicostemma. All animals had free access to water and standard pellets of. Antioxidant and hepatoprotective effect of swetiamarin from enocostemma axillare against dgalactosamine induced acute liver damage in rats. Hepatoprotective activity of enicostemma axillare in paracetamol. Karthikeyan department of zoology, presidency college autonomous, chennai600005, tamil nadu, india corresponding author a b s t r a c t antibacterial inhibition. Antiedematogenic and free radical scavenging activity of. A comprehensive assessment of the biological activities of different extracts is included and possible mechanisms and phytochemicals.
Raynal by centrifugal partition chromatography and nuclear magnetic resonancemass spectrometry article pdf available. Four successive extracts of the whole plant of enicostemma axillare e. Antioxidant activity or free radical scavenging activity of. Free radical and reactive oxygen species are well known inducers of cellular and. Methanol extract of whole plant of enicostemma axillare family.
Phytochemical profiling, antibacterial potential and gcms. A small molecule swertisin from enicostemma littorale differentiates nih3t3 cells into isletlike clusters. It was found to be affected by a witches broom disease under the field conditions at anand, gujarat, india. Phytochemical and pharmacognostic value of enicostemma littorale. Ashwini kumar sharma abstract ayurveda uses the inherent power of natural herbs to bring out wonderful results on the human body. Materials and methods plant material the whole plants of enicostemma axillare were collected in fresh condition from coimbatore region of western ghats, tamilnadu. The surface plasmon resonance band at 442 nm in the uvvisible absorption spectra strongly affirms the development of ag nps in the aqueous medium. Acute and subacute toxicity study of aqueous extracts of. Arnold, buy draughtsmanship by ronald fraser reekie from waterstones today. Preliminary study on antifertility activity of enicostemma. Enicostemma axillare is used in indian traditional medicine as a liver tonic. Mamejvo enicostemma axillare raynal is a perennial herb with diversified health benefits.
Enicostemma axillare by inhibition of albumin denaturation, antiproteinase action, membrane stabilization and antilipoxygenase activity. Raynal is used in traditional practice for the treatment of diabetes, malaria and liver disorders. Present study aimed for molecular docking, antiproliferative and anticonvulsant activities of swertiamarin isolated from the successive methanol extract of enicostemma axillare. Phytochemical screening and invitro antioxidant activities of. Antioxidant and hepatoprotective effect of the ethyl. Separation and identification of swertiamarin from enicostema axillare lam. Enicostema axillare in the germplasm resources information network grin, u.
Pdf antibacterial activity of enicostemma axillare. A small molecule swertisin from enicostemma littorale differentiates. In this work, an ecofriendly and cost effective green synthesis has been employed to the fabrication of silver nanoparticles ag nps from the nontoxic aqueous gymnema sylvestre leaf extract as a reducing agent. Four successive extracts of whole plant of enicostemma axillare were examined for in vitro antioxidant activity using nine different methods. Pdf separation and identification of swertiamarin from. This study investigated the antiacne activity of phloretin against propionibacterium acnesinduced skin infection and the potential target proteins of its antiinflammatory and antibacterial effects. Enicostemma axillare of plants showed presence of cardiac glycosides in leaf and root, reducing sugar higher in leaf, steroids relatively higher in leaf and flower, high levels of. Hence, in the present study, the effect of enicostemma axillare extract on the migration of mcf7 cell lines using western blotting was evaluated.
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